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Prof. James Adams

2025 Presentation(s):

Toxic Microbial Metabolites in Autism and Treatment with Microbiota Transplant Therapy

The presentation will begin In:

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Abstract

Our new discovery is that approximately 90% of children with autism have extremely elevated toxic metabolites from their gut bacteria and yeast, compared to 0% of healthy typical children.  The effects of these toxins and how to test for them will be discussed.    A summary of three major research studies of microbiota transplant therapy for autism will be discussed, along with plans for current and future studies.

P-Cresol and Indoxyl Sulfate

The presentation will begin In:

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Abstract
P-cresol and indoxyl sulfate are two microbially-derived metabolites that many studies have found are significantly higher in urine of children with autism compared to typically-developing children.  These metabolites have many toxic effects on the body and brain, and cause autistic symptoms when administered to animals.  This presentation will summarize the effects of these metabolites on body and brain function and their relationship to autism.
Speaker Bio:

James B. Adams, Ph.D., is the Director of the Autism/Asperger’s Research Program at Arizona State University. His research focuses on the medical causes of autism and how to treat and prevent it including the areas of nutrition, gut bacteria, and microbiota transplant.   He has published over 180 peer-reviewed scientific articles, including over 60 related to autism.  He is the President of the non-profit Autism Nutrition Research Center, President of Autism Diagnostics, and President of Gut-Brain-Axis Therapeutics

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